Only one coin may appear from the US Mint as part of the 2021 America the Beautiful Silver Uncirculated Coins assuming there is only one 2021 America the Beautiful Silver Bullion Coin. That is because the associated bullion series is scheduled to complete its run of fifty-six five ounce .999 fine silver strikes that year with the release of only one issue.
However, when Congress authorized the America the Beautiful Silver Bullion Coins™ Program (of which these silver uncirculated coins are struck to be the collector grade versions of), it also allowed for the possibility of a second complete series of fifty-six bullion coins to immediately follow the first. The decision to continue the series is left to the Treasury of the Secretary who must inform Congress of the plans by the end of the ninth year of the original program which debuted in 2010.
The US Mint is under no such direct obligation with these five ounce silver uncirculated coins because they were not directly authorized by Congress. Instead, they were created under the authority granted the Treasury Secretary in 31 U.S.C. §5111(a) (3). They were designed to be the numismatic versions of the Congressionally mandated bullion coins.
However, if the bullion coins are continued for a second run, and assuming these uncirculated coins have proven to sell well, it is likely that the US Mint would continue this series as well.
Brief information for the only 2021 America the Beautiful Five Ounce Uncirculated Silver Coin currently known to be struck follows. Additional details for the coin may be found by following the provided link.
2021 Tuskegee Airmen 5 Ounce Silver Uncirculated Coins
The 2021 Tuskegee Airmen Silver Uncirculated Coins will be struck by the US Mint with a reverse design honoring the Tuskegee Airmen National Historic Site of Alabama. This coin may mark the last of the series which debuted with 2010-dated strikes unless continued at the discretion of the Treasury Secretary.
Consisting of a relatively small 44.71 acres, Congress established the national historic site on November 6, 1998. It was created to honor the service provided by African American Airmen during World War II.
A site dedicated to the series can be found by clicking 5 oz silver coins.